Open AccessSynthesis, Characterization and Bioactivities of Some Novel Oxovanadium(IV) Glycinato Complexes
Author(s) -
Mohammad K. Islam,
Md Nuruzzaman,
Rashedul I. Ripon,
Md. Shalauddin,
Foni B. Biswas,
M. Mofazzal Hossain,
Mohammad K. Islam,
Sumaiya Khan
Publication year - 2018
Publication title -
european scientific journal
Language(s) - English
Resource type - Journals
eISSN - 1857-7881
pISSN - 1857-7431
DOI - 10.19044/esj.2018.v14n21p410
Subject(s) - chemistry , vanadium , pyocyanin , denticity , stereochemistry , antibacterial activity , in vivo , square pyramidal molecular geometry , brine shrimp , chelation , nuclear chemistry , bacteria , crystallography , organic chemistry , biochemistry , biology , crystal structure , virulence , ecology , quorum sensing , genetics , microbiology and biotechnology , gene
The novel oxovanadium(IV) complexes, [VIVO(GlyH)(Gly)]+ClO4 - .H2O (1), [VIVO(GlyH)(Gly)]+NO3 - .H2O (2), [VIVO(GlyH)(Gly)]+CH3COO- .H2O (3) were synthesized and characterized by FT-IR, UV-Vis and 1H NMR spectroscopic measurements. The cumulative spectroscopic assessment envisaged that, the complexes adopt a square pyramidal structure, in which the two glycine ligands coordinate to vanadium(IV) center in bidentate fashions conforming a homoleptic structure. The amino nitrogen and a carboxylato oxygen atom coordinate the vanadium(IV) center from both sides making a five members chelate by each side. All the complexes are stable in amorphous state and in aerobic and anaerobic solution. Significantly, all the complexes have the antifungal activities against Aspergillus niger and Penicillium notatum but ineffective against Candida tropicalis. No antibacterial activity was observed for the complexes against tested bacteria and unfortunately, they were found cytotoxic against brine shrimp bioassay.