Open AccessActivité Anti-Hyperglycémiante Et Élucidation Structurale Des Composés Isolés Des Feuilles De Spondias Purpurea L. (Anacardiaceae)
Author(s) -
Armel Diatta,
Anastasie Manga,
Abdoulaye Gassama,
Catherine Lavaud
Publication year - 2017
Publication title -
european scientific journal
Language(s) - English
Resource type - Journals
eISSN - 1857-7881
pISSN - 1857-7431
DOI - 10.19044/esj.2017.v13n36p312
Subject(s) - anacardiaceae , phytochemical , traditional medicine , kaempferol , quercetin , tannin , chemistry , botany , biology , biochemistry , medicine , antioxidant
Spondias purpurea L. (Anacardiaceae) is a Senegalese traditional pharmacopoeia plant, which leaves are used in the treatment of various diseases. The leaves’ ethanolic extract exhibited antihyperglycemic activity on models of temporary hyperglycemia. The tests were performed on normoglycemic rats with a glucose tolerance test. The phytochemical investigation of the leaves resulted in the isolation of four flavonoids (quercetin 9, kaempferol 10, quercetin-3- ß-glucopyranoside 6, kaempferol3-ß-galactopyranoside 8), five phenolic compounds (2,4-dihydroxybenzoic acid 2, 4-hydroxybenzoic acid 5, protocatechic 4-ß-glucoside acid 1, hydroxycynnamic acid 7, 5-caffeoylquinic acid 3) and one tannin (Strictinin 4). The known isolated compounds were characterized by NMR and massspectrometry. The present study constitutes the first phytochemical examination of the leaves and the anti-hyperglycemic activity of the ethanolic extract of Spondias Purpurea L.