Open AccessEtude Ethnobotanique, Evaluation De L’activite Antifongique Sur Candida Albicans Et De La Toxicite Sur Des Cellules Hff De Bersama Abyssinica (Fresen.), Une Plante De La Pharmacopee Ivoirienne
Author(s) -
Djeneb Camara,
Kouadio Béné,
Gnahoué Goueh,
N’Guessan Bra Yvette Fofie,
Guédé Noël Zirihi
Publication year - 2016
Publication title -
european scientific journal
Language(s) - English
Resource type - Journals
eISSN - 1857-7881
pISSN - 1857-7431
DOI - 10.19044/esj.2016.v12n3p171
Subject(s) - candida albicans , traditional medicine , ic50 , in vitro , corpus albicans , microbiology and biotechnology , biology , chemistry , medicine , biochemistry
To make a contribution to the fight against opportunistic mycoses in sharp increase in AIDS patients, we conducted an ethnobotanical investigation in the Department of Transua (Côte d’Ivoire). This investigation has shown that the plant Bersama abyssinca is the most used in the treatment of skin infection. Our team tested different extracts of leaves of B. abyssinica (aqueous extract total (ETA), 70% ethanol extract (EE70%) and aqueous extract residual (ERA)) on the in vitro growth of Candida albicans, to determine some inhibitions parameters. These three extracts were active in C. albicans, with respective IC50: 160 μg/ml for ETA, 100 μg/ml for EE70% and 55 μg/ml for ERA. We found that B. abyssinica is not toxic for human cells HFF, on the contrary, it increases the proliferation of dividing cells thereby improving defense mechanisms.