Open AccessPhysiological Interactions Of Calcium And Vitamin D In Colon
Author(s) -
Ahmed Abu-Zaiton,
Ahed J Alkhatib,
Suha Khaiery Ababneh,
Faisal Kanaan
Publication year - 2016
Publication title -
european scientific journal
Language(s) - English
Resource type - Journals
eISSN - 1857-7881
pISSN - 1857-7431
DOI - 10.19044/esj.2016.v12n24p49
Subject(s) - calcium , vitamin d and neurology , vitamin , calcium metabolism , carcinogenesis , medicine , colorectal cancer , calcium binding protein , endocrinology , calcium supplementation , biology , cancer
This study aimed to review the literature about possible physiological interactions of calcium and vitamin D in colon. Previous studies have indicated to protective effects of vitamin D and calcium in case of colon cancers. We wanted to check the physiological effects of both of vitamin D and calcium, and either of each of them alone. We suggested effects of metabolism through induction of changes in the levels of various biomarkers that have influences in carcinogenesis including p53, heat shock proteins, iNOS and WT1 gene.