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Association Between Periodontitis and Chronic Obstructive Pulmonary Disease in a Chinese Population
Author(s) -
Si Yan,
Fan Hong,
Song Yiqing,
Zhou Xuan,
Zhang Jing,
Wang Zuomin
Publication year - 2012
Publication title -
journal of periodontology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.036
H-Index - 156
eISSN - 1943-3670
pISSN - 0022-3492
DOI - 10.1902/jop.2012.110472
Subject(s) - medicine , bode index , copd , periodontitis , periodontal examination , dental alveolus , body mass index , clinical attachment loss , population , odds ratio , gastroenterology , chronic periodontitis , pulmonary function testing , pulmonary rehabilitation , dentistry , environmental health
Background: A relationship between periodontitis and chronic respiratory disease has been suggested by recent studies. The aim of this study is to explore the association between periodontitis and chronic obstructive pulmonary disease (COPD) in a Chinese population. Methods: We conducted a case‐control study of 581 COPD cases and 438 non‐COPD controls. Lung function examination, a 6‐minute walk test, and the British Medical Research Council questionnaire were performed. Periodontal clinical examination index included probing depth (PD), attachment loss (AL), bleeding index (BI), plaque index (PI), and alveolar bone loss. A validated index for predicting COPD prognosis, the body mass index, airflow obstruction, dyspnea, and exercise capacity (BODE) index, was also calculated. Results: Participants with more severe COPD were more likely to have severe periodontal disease. PD, AL, PI, alveolar bone loss, and the number of teeth were significantly associated with all stages of COPD (all P <0.001). When compared to controls (BODE = 0), participants with higher BODE scores had significantly higher AL ( P <0.001), BI ( P = 0.027), PI ( P <0.001), alveolar bone loss ( P <0.001), and the number of teeth ( P <0.001). PI appeared to be the main periodontal health‐related factor for COPD, with an odds ratio (OR) = 9.01 (95% CI = 3.98 to 20.4) in the entire study population OR = 8.28 (95% CI = 2.36 to 29.0), OR = 5.89 (95% CI = 2.64 to 13.1), and OR = 2.46 (95% CI = 1.47 to 4.10) for current, smokers, and non‐smokers, respectively. Conclusion: Our study found a strong association between periodontitis and COPD, and PI seemed to be a major periodontal factor for predicting COPD among Chinese adults.