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Effects of Bioactive Glass on Bone Augmentation Within a Titanium Cap in Rabbit Parietal Bone
Author(s) -
Nishida Tetsuya,
Yamada Yutaka,
Murai Masakazu,
Shimizu Yuka,
Oshikawa Maiko,
Ito Koichi
Publication year - 2006
Publication title -
journal of periodontology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.036
H-Index - 156
eISSN - 1943-3670
pISSN - 0022-3492
DOI - 10.1902/jop.2006.050170
Subject(s) - rabbit (cipher) , parietal bone , bioactive glass , chemistry , dentistry , anatomy , medicine , computer science , skull , computer security
Background: The condition of alveolar bone influences the success and subsequent esthetics of implant treatment. This study investigated the early effects of bioactive glass (BG) on bone augmentation within a hemispherical titanium cap in rabbit parietal bone. Methods: Twelve adult male Japanese white rabbits were used. One titanium cap (test site) was packed with BG in a collagen gel, and the other (control site) was packed with the collagen gel alone. After 1 and 3 months, animals were euthanized, and the experimental area was examined using fluorescence and light microscopy. Results: Newly generated bone was observed at 1 and 3 months of healing. Although bone was also generated without BG, newly mineralized bone was generated sooner with BG present for guided bone augmentation than without BG. At 1 and 3 months, the BG was not bioabsorbed completely, and some particles remained. Conclusion : New bone is generated at an early stage of bone formation using BG for bone augmentation.