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Effect of Non‐Surgical Periodontal Therapy on Glycemic Control in Patients with Type 2 Diabetes Mellitus
Author(s) -
Rodrigues Débora C.,
Taba Mário,
Novaes Arthur B.,
Souza Sérgio L.S.,
Grisi Márcio F.M.
Publication year - 2003
Publication title -
journal of periodontology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.036
H-Index - 156
eISSN - 1943-3670
pISSN - 0022-3492
DOI - 10.1902/jop.2003.74.9.1361
Subject(s) - glycemic , medicine , glycated hemoglobin , scaling and root planing , statistical significance , type 2 diabetes mellitus , diabetes mellitus , gastroenterology , amoxicillin , periodontitis , metabolic control analysis , clinical attachment loss , bleeding on probing , dentistry , type 2 diabetes , chronic periodontitis , insulin , endocrinology , antibiotics , microbiology and biotechnology , biology
Background: The literature suggests that an alteration in glucose metabolism occurs as a result of antibacterial periodontal therapy. The objective of this study was to monitor the effect of non‐surgical periodontal therapy on glycemic control in patients with type 2 diabetes mellitus (DM). Methods: Thirty type 2 DM subjects with periodontitis were randomly divided into two groups. Group 1 (G1), 15 subjects, received one‐stage full‐mouth scaling and root planing (FMSRP) plus amoxicillin/clavulanic acid 875 mg; group 2 (G2), 15 patients, received only FMSRP. At baseline and after 3 months, the glycated hemoglobin (HbA 1c ) values, fasting glucose, and clinical parameters (with computerized probing and individualized acrylic stents) were recorded. Following therapy, the subjects were enrolled in a 2‐week interval maintenance program for 3 months. Results: After treatment, both groups showed clinical improvements. A probing depth (PD) reduction of 0.8 ± 0.6 mm ( P <0.05) occurred in G1 and 0.9 ± 0.4 mm in G2 ( P <0.05), but there were no significant changes in attachment level. Treatment reduced the HbA1c values after the 3‐month observation period in both groups; however, the reduction in HbA 1c values for the G2 group was statistically significant, but not for the G1 group. The changes in fasting glucose levels were not significant for either group. Conclusions: Periodontal therapy improved glycemic control in patients with type 2 DM in both groups; however, the reduction in HbA1c values reached statistical significance only in the group receiving scaling and root planing alone. J Periodontol 2003;74:1361‐1367 .