Minocycline‐Induced Staining of Torus Palatinus and Alveolar Bone

Background: Minocycline hydrochloride, an analog of tetracycline, is widely used in the treatment of acne. Its use has been associated with discoloration of teeth, bone, and other tissues . Methods: A case is presented involving a patient with minocycline‐induced staining of the torus palatinus and alveolar bone . Results: No treatment was rendered since the patient was not concerned with the appearance of the discoloration. The patient's dermatologist elected to change antibiotics . Conclusions: Patients on long‐term minocycline therapy should be made aware of the possibility of pigmentation of bone and soft tissue that may be reversible with discontinuation of therapy; however, minocycline‐induced staining of the permanent dentition may not be reversible . J Periodontol 2003;74:669‐671.