Premium
Informational Paper: Modulation of the Host Response in Periodontal Therapy
Author(s) -
Richard J. Oringer
Publication year - 2002
Publication title -
journal of periodontology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.036
H-Index - 156
eISSN - 1943-3670
pISSN - 0022-3492
DOI - 10.1902/jop.2002.73.4.460
Subject(s) - periodontology , periodontal disease , pathogenesis , matrix metalloproteinase , host response , immune system , immune modulation , medicine , arachidonic acid , periodontium , dentistry , immunology , biology , enzyme , biochemistry
This paper was prepared by the Research, Science, and Therapy Committee of the American Academy of Periodontology to provide the dental profession an overview of current and potential methods to modulate the host response in the treatment of periodontal diseases. Specifically, it discusses components of periodontal disease pathogenesis (i.e., immune and inflammatory responses, excessive production of matrix metalloproteinases and arachidonic acid metabolites, and regulation of bone metabolism) and their modulation. J Periodontol 2002;73:460‐470.