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Langerhans' Cell Histiocytosis Diagnosed Through Periodontal Lesions: A Case Report
Author(s) -
Muzzi Leonardo,
Prato Giovan Paolo Pini,
Ficarra Giuseppe
Publication year - 2002
Publication title -
journal of periodontology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.036
H-Index - 156
eISSN - 1943-3670
pISSN - 0022-3492
DOI - 10.1902/jop.2002.73.12.1528
Subject(s) - langerhans cell histiocytosis , medicine , diabetes insipidus , pathology , histiocytosis , disease
Background: Langerhans' cell histiocytosis (LCH) is a rare disorder in which a neoplastic proliferation of cells similar to the Langerhans' cell of the epidermis is observed. The disease may affect different organs as solitary or multiple lesions with a complete dissemination in different organs such as the bone (jaws), lung, hypothalamus, skin and mucous membranes, lymph nodes, liver, and other tissues. Although LCH is considered a childhood or juvenile disease, the diagnosis is often made in adults, and in many cases, a juvenile form progresses into adult life. Hand‐Schuller‐Christian disease (HSCD) is an LCH form in which the typical lesions involve the cranial bones, the eyes, and the pituitary gland.Methods: This article describes a case of a patient diagnosed, through periodontal lesions and diabetes insipidus, as having Langerhans' cell histiocytosis.Conclusion: As far as LCH lesions appearing in periodontal tissues, the periodontist should be involved in the detection of oral lesions. J Periodontol 2002;73:1528‐1533.