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Gingival Plasma Cell Granuloma
Author(s) -
Peacock Mark E.,
Hokett Steven D.,
Hellstein John W.,
Herold Robert W.,
Matzenbacher Scott A.,
Scales Donald K.,
Cuenin Michael F.
Publication year - 2001
Publication title -
journal of periodontology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.036
H-Index - 156
eISSN - 1943-3670
pISSN - 0022-3492
DOI - 10.1902/jop.2000.72.9.1287
Subject(s) - plasma cell granuloma , pathology , plasma cell , biopsy , medicine , granuloma , immunohistochemistry , pyogenic granuloma , lesion , inflammatory pseudotumor , bone marrow
Plasma cell granulomas (pseudotumors) are rare benign, tumor‐like proliferations composed chiefly of plasma cells that manifest primarily in the lungs, but may occur in various anatomic locations. We report this case of a 54‐year‐old male who presented with an unusual maxillary anterior gingival overgrowth treated by excisional biopsy. Histological examination revealed a dense inflammatory cell infiltrate containing mainly plasma cells. Immunohistochemistry for kappa and lambda light chains showed a polyclonal staining pattern confirming a diagnosis of plasma cell granuloma. Intraoral plasma cell granuloma is exceedingly rare, although case reports documenting such lesions have been reported. This case highlights the need to biopsy unusual lesions to rule out potential neoplasms. J Periodontol 2001;72:1287‐1290.