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Guided Tissue Regeneration With a Bioabsorbable Polylactic Acid Membrane in Gingival Recessions. A Histometric Study in Dogs
Author(s) -
Casati Marcio Z.,
Sallum Enilson A.,
Caffesse Raul G.,
Nociti Francisco H.,
Sallum Antonio Wilson,
da Silva Pereira Sergio L.
Publication year - 2000
Publication title -
journal of periodontology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.036
H-Index - 156
eISSN - 1943-3670
pISSN - 0022-3492
DOI - 10.1902/jop.2000.71.2.238
Subject(s) - cementum , connective tissue , junctional epithelium , medicine , buccal administration , polylactic acid , regeneration (biology) , dentistry , gingival recession , anatomy , pathology , chemistry , biology , microbiology and biotechnology , polymer , organic chemistry , dentin
Background: The goal of this investigation was to histologically and histometrically evaluate the healing process of gingival recessions treated by guided tissue regeneration with bioabsorbable polylactic acid membranes (GTR group) and to compare it to that obtained with coronally positioned flaps (CPF group). Methods: Gingival recessions were surgically created on the buccal aspect of the upper cuspids of 5 mongrel dogs. The defects (5×7 mm) were exposed to plaque accumulation for 3 months. The contralateral defects were then randomly assigned to each group. After 3 months of healing, the dogs were sacrificed and the blocks were processed. The histometric parameters evaluated included length of sulcular and junctional epithelium, connective tissue adaptation, new cementum, new bone, and defect coverage. Results: The extension of the epithelium was 1.9 ± 0.8 mm for the GTR‐group and 3.0 ± 0.9 mm for the CPF‐group ( P = 0.16). The connective tissue adaptation was 0.1 ± 0.1 and 0.8 ± 0.5 mm in the GTR group and CPF group, respectively ( P = 0.051). The new cementum was 3.8 ± 1.5 mm and 2.4 ± 0.3 mm in the GTR group and CPF group, respectively ( P = 0.16). Bone formation was 1.1 ± 0.5 mm in the GTR group and 1.4 ± 0.2 mm in the CPF group ( P = 0.53). Histologically, the defect coverage observed was similar, 90.5% and 91.9% for the GTR group and the CPF group, respectively. No statistical differences in any of the parameters could be detected. Conclusions: Within the limits of this study, it can be concluded that both procedures resulted in a favorable healing response with no significant difference between the treatments. J Periodontol 2000;71:238‐248.