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Calprotectin and Lactoferrin Levels in the Gingival Crevicular Fluid of Children
Author(s) -
Miyasaki Kenneth T.,
Voganatsi Alexandra,
Huynh Thuc,
Marcus Marvin,
Underwood Steven
Publication year - 1998
Publication title -
journal of periodontology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.036
H-Index - 156
eISSN - 1943-3670
pISSN - 0022-3492
DOI - 10.1902/jop.1998.69.8.879
Subject(s) - lactoferrin , calprotectin , medicine , population , dentistry , gastroenterology , chemistry , biochemistry , disease , inflammatory bowel disease , environmental health
T he purpose of this study was to determine the levels of calprotectin and lactoferrin, 2 microbiostatic proteins, in the gingival crevicular fluid (GCF) of normal children. The children represented a population, primarily underprivileged, seeking care at a regional dental health care center. GCF was collected from Ramfjord teeth (or their deciduous equivalent). GCF volume was quantified by conductance. Calprotectin and lactoferrin levels were quantified by sandwich ELISA, and found to have a mean value of 70.8 ± 94.2 μg/mL and 68.2 ± 108.7 μg/mL, respectively. The levels of calprotectin and lactoferrin varied directly with one another and inversely with the amount of fluid obtained in a 20‐second sampling period. The mean levels were at or above the minimum inhibitory concentration determined in vitro. J Periodontol 1998;69:879–883 .