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Microbiota Associated With Experimental Peri‐Implantitis and Periodontitis in Adult Macaca mulatta Monkeys
Author(s) -
Eke Paul I.,
Braswell Laura D.,
Fritz Michael E.
Publication year - 1998
Publication title -
journal of periodontology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.036
H-Index - 156
eISSN - 1943-3670
pISSN - 0022-3492
DOI - 10.1902/jop.1998.69.2.190
Subject(s) - peri implantitis , periodontitis , medicine , dentistry , surgery , implant
T his study examines the microbiota associated with the progression of experimental peri‐implantitis and periodontitis induced concurrently in partially edentulous adult monkeys. Root‐form and plate‐form implants with fixed prosthesis in place for at least 12 months and their corresponding opposite molar teeth were ligated for 6 months. The microbiota in plaque around these ligated dental implants and molars were studied at 0, 1, 2, 3, and 6 months post‐ligation. Plaque samples were analyzed by dark‐field microscopy and selective and non‐selective culture. Putative periodontal pathogens were detected as a major component of the microbiota cultured from plaque samples obtained from experimental peri‐implantitis sites. Overall, the types and relative proportions of putative periodontal pathogens in plaque associated with ligature‐induced peri‐implantitis and ligature‐induced periodontitis were similar. Only levels of anaerobic Actinomyces and spirochetes were significantly different between both sites. Spirochete levels were significantly higher at peri‐implantitis sites when compared with levels at periodontitis sites after 6 months, and spirochete levels increased significantly between 0 and 6 months post‐ligation at implant sites. Levels of spirochetes correlated significantly with probing depth and bone loss at peri‐implantitis sites. Overall, Actinomyces levels were higher at periodontitis sites. Porphyromonas species were not detected continuously as part of the peri‐implantitis microbiota. In conclusion, this study finds that the microbiota associated with the progression of experimental periimplantitis and periodontitis occurring concurrently in partially edentulous mouths are similar. J Periodontol 1998;69:190–194 .