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Periodontal Management of Glanzmann's Thrombasthenia: Report of 3 Cases
Author(s) -
Kantorci Alpdoǧan,
Cebeci Irfan,
Firatli Erhan,
Atamer Tanju,
Tuncer Özen
Publication year - 1996
Publication title -
journal of periodontology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.036
H-Index - 156
eISSN - 1943-3670
pISSN - 0022-3492
DOI - 10.1902/jop.1996.67.8.816
Subject(s) - glanzmann's thrombasthenia , thrombasthenia , medicine , platelet , mucocutaneous zone , clot retraction , periodontal disease , platelet membrane glycoprotein , pediatrics , dermatology , dentistry , disease , platelet aggregation
G lanzmann's thrombasthenia was reported and described as a bleeding diathesis seen in children and characterized by diminished clot retraction. It is an autosomal recessive bleeding disorder. The disease is marked by frequent mucocutaneous hemorrhages either due to defective function of the platelets or lack of fibrinogen binding membrane receptor glycoproteins IIb/IIIa which are located on the surface of the platelets. Case reports on 3 siblings, a girl of 11, and 2 boys of 12 and 16 years old with Glanzmann's thrombasthenia are reviewed. The major complaint of the patients was gingival bleeding. Periodontal treatment was performed under platelet transfusion and proper oral hygiene instruction was given. The patients were followed for 6 months and no periodontal complications developed during this time. Proper periodontal care for such patients is essential both for local and systemic health. J Periodontol 1996;67:816–820 .