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The Role of the Host Response in Periodontal Disease Progression: Implications for Future Treatment Strategies
Author(s) -
Van Dyke Thomas E.,
Lester Mary Ann,
Shapira Lior
Publication year - 1993
Publication title -
journal of periodontology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.036
H-Index - 156
eISSN - 1943-3670
pISSN - 0022-3492
DOI - 10.1902/jop.1993.64.8s.792
Subject(s) - periodontal disease , periodontitis , immune system , host response , immunology , function (biology) , macrophage , complement (music) , medicine , disease , focus (optics) , regeneration (biology) , host factors , biology , pathology , dentistry , microbiology and biotechnology , biochemistry , virus , physics , complementation , gene , optics , in vitro , phenotype
I n this paper, we review the relevant aspects of host responses in periodontal diseases as we understand them today. Discussion will focus on neutrophil function, lymphocytes and the immune response, macrophage function, cytokines and complement, fibroblasts and growth factors, and regeneration. Recent literature and concepts will be presented with an emphasis on future directions and application to treatment regimens. J Periodontol 1993; 64:792–806 .