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Periodontal Disease in Three Siblings With Familial Neutropenia
Author(s) -
Kirstilä Varpuleena,
Sewón Lüsi,
Laine Juhani
Publication year - 1993
Publication title -
journal of periodontology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.036
H-Index - 156
eISSN - 1943-3670
pISSN - 0022-3492
DOI - 10.1902/jop.1993.64.6.566
Subject(s) - medicine , neutropenia , periodontal disease , periodontitis , congenital neutropenia , oral hygiene , disease , dentistry , chemotherapy
T he periodontal status and treatment of three teenagers in a Finnish family with familial neutropenia is described. The mother was also diagnosed with neutropenia. At initial examination, the 15‐year‐old male and the 10‐year‐old female had severe periodontitis, whereas the 13‐year‐old male had oral ulcerations but no significant periodontal disease. The two siblings with periodontitis were treated and followed approximately 5 years. It was concluded that periodontal therapy including scaling, surgery, and use of antimicrobial agents can be successful in patients with familial neutropenia, and that such patients are not necessarily candidates for full mouth extraction. The role of granulocyte colony‐stimulating factor in which was used in the treatment of these patients remains to be established. J Periodontol 1993;64:566–570.