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Evaluation of Ferric Oxalate as an Agent for Use During Surgery to Prevent Post‐Operative Root Hypersensitivity
Author(s) -
Wang HomLay,
Yeh ChiTsai,
Smith Frederic,
Burgett Frederick G.,
Richards Philip,
Shyr Yu,
O'Neal Robert
Publication year - 1993
Publication title -
journal of periodontology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.036
H-Index - 156
eISSN - 1943-3670
pISSN - 0022-3492
DOI - 10.1902/jop.1993.64.11.1040
Subject(s) - saline , medicine , analysis of variance , dentistry , visual analogue scale , oxalate , dentin hypersensitivity , repeated measures design , ferric , surgery , anesthesia , dentin , chemistry , mathematics , statistics , organic chemistry
T he aim of this study was to evaluate the effectiveness of a 6% ferric oxalate solution applied during periodontal surgery to prevent post‐operative tooth hypersensitivity. Twenty‐five adult patients with similar bilateral periodontal defects participated in this study. Data were collected at baseline (1 week prior to surgery) and 1, 2, 4, and 6 weeks following surgery. Sensitivity level was determined using the visual analog scale (VAS) with the following stimuli: 1) mechanical stimulation with a No. 23 dental explorer; 2) water at 50°C; 3) ice; and 4) electric pulp tester (EPT). Teeth were randomly assigned to either test (6% ferric oxalate in 0.9% saline) or control (0.9% saline) groups. Solutions were applied to the exposed root surfaces for 1 minute during surgery. Data were analyzed by repeated measures ANOVA, paired t ‐test, and Pearson's correlation test. Results from this study demonstrated statistically significant reduction in the responses to thermal stimuli, especially cold, between groups treated with ferric oxalate as compared to those treated with saline. For the cold test the difference increased with time from baseline to 6 weeks. Statistically significant ( P <0.05) differences in sensitivity to heat between groups were also observed, but only at 2 and 4 weeks following surgery. There were no differences at any time period between the test and control groups when tactile or EPT techniques were used. In addition, there was no correlation between sensitivity and other clinical parameters. It was concluded from this study that 6% ferric oxalate was effective in reducing post‐surgical cold sensitivity when applied during periodontal surgical procedures. J Periodontol 1993; 64:1040–1044.