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Clinical Documentation and Occurrence of Putative Periodontopathic Bacteria in Human Immunodeficiency Virus‐Associated Periodontal Disease
Author(s) -
Gornitsky Mervyn,
Clark D. Christopher,
Siboo Russell,
Amsel Rhonda,
Lugovaz Irene,
Wooley Christine,
Luliani Nathalie,
Chan Eddie C. S.
Publication year - 1991
Publication title -
journal of periodontology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.036
H-Index - 156
eISSN - 1943-3670
pISSN - 0022-3492
DOI - 10.1902/jop.1991.62.9.576
Subject(s) - gingivitis , periodontium , periodontitis , human immunodeficiency virus (hiv) , medicine , immunology , biology , dentistry
H uman immunodeficiency virus (hiv)‐associated gingivitis (HIV‐G) and HIVassociated periodontitis (HIV‐P) are two intraoral lesions manifested by patients with HIV infection. Periodontal indices were measured for 87 subjects in 5 study groups: HIV‐seropositive patients with healthy periodontium (HIV‐H), with HIV‐G, or with HIVP; and non‐HIV‐infected subjects with healthy periodontium (H) or with adult chronic periodontitis (P). The quantitative clinical parameters were compared and statistically significant intergroup differences were noted. The mean scores on PI and PD do not discriminate between HIV‐seropositive and non‐HIV‐infected seronegative cohorts, but a significant difference in the GI between HIV‐H and H was noted. When categories of PD and AL are examined, some differences become apparent. Generally, the PD and AL of HIV‐P are not as great as those of P. PI correlates well with GI (r = 0.86) in P, but does not (r = 0.33) in HIV‐P. In addition, the occurrence of selected putative periodontopathic bacteria ( Porpfiyromonas gingivalis , spirochetes, and motile eubacteria) in these lesions was determined by brightfield (after staining), darkfield and immunofluorescent microscopy. No difference in microbiological profile in the bacterial groups monitored was found between P and HIV‐P. Spirochetes were found to be more abundant than P. gingivalis in the lesions of P and HIV‐P. In marked contrast, P. gingivalis was found to be in highest numbers in samples from the gingival crevice of H as determined by indirect immunofluorescence. J Periodontol 1991; 62:576–585.