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A Critical Review of the Biologic Rationale for Guided Tissue Regeneration
Author(s) -
Minabe Masato
Publication year - 1991
Publication title -
journal of periodontology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.036
H-Index - 156
eISSN - 1943-3670
pISSN - 0022-3492
DOI - 10.1902/jop.1991.62.3.171
Subject(s) - regeneration (biology) , medicine , tissue repair , wound healing , dentistry , surgery , biology , biomedical engineering , microbiology and biotechnology
T his review discusses the rationale for using guided tissue regeneration therapy. The review not only attempts to clarify the concept of selective tissue regeneration using non‐resorbable and resorbable barriers, but to discuss differences in healing events after treatment with the two types of barriers together with their significance in periodontal therapy. At present, barrier membranes have potential clinical use in promoting periodontal tissue regeneration if patients to be so treated are selected appropriately. Research is still necessary to determine the critical period for guiding the ingrowth of new attachment forming cells and also to further clarify the concept of GTR involving the “wrong cell type” which inhibits periodontal tissue regeneration. J Periodontol. 1991; 62:171– 179 .