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Total Hemolytic Complement (CH50) and Its Fractions (C3 and C4) in the Sera of Diabetic Patients With Periodontitis
Author(s) -
Anil S.,
Remani P.,
Vijayakumar T.,
Joseph Preethi A.
Publication year - 1990
Publication title -
journal of periodontology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.036
H-Index - 156
eISSN - 1943-3670
pISSN - 0022-3492
DOI - 10.1902/jop.1990.61.1.27
Subject(s) - periodontitis , medicine , diabetes mellitus , complement (music) , endocrinology , gastroenterology , biology , biochemistry , complementation , gene , phenotype
T he total hemolytic complement activity (CH50) and its fractions C3 and C4 were determined in 50 patients with Type II or non‐insulin dependent diabetes mellitus (NIDDM) and 50 nondiabetic patients with periodontitis. The values were compared with those of 50 age and sex matched controls. An elevation of CH50 was observed in both the diabetic and nondiabetic patients, compared to controls. The diabetic patients with periodontitis showed a significantly higher complement activity compared to nondiabetic patients with periodontitis. The C3 and C4 values were significantly elevated in both diabetic and nondiabetic patients when compared with the control group. The elevation being more pronounced in diabetic groups. J Periodontol 1990;61:27–29.