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Effect of a Chemotherapeutic Agent Delivered by an Oral Irrigation Device on Plaque, Gingivitis, and Subgingival Microflora
Author(s) -
Ciancio Sebastian G.,
Mather Maryanne L.,
Zambon Joseph J.,
Reynolds Homer S.
Publication year - 1989
Publication title -
journal of periodontology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.036
H-Index - 156
eISSN - 1943-3670
pISSN - 0022-3492
DOI - 10.1902/jop.1989.60.6.310
Subject(s) - gingivitis , medicine , dentistry , dental plaque , gingival and periodontal pocket , periodontal disease
S ixty‐six adults were examined in a double‐blind study which examined the effect of an antimicrobial agent delivered by an oral irrigating device. Each subject received a randomized half mouth dental prophylaxis. The Gingival Index, gingival crevicular fluid volume, Plaque Index, Modified Papillary Bleeding Index, probing pocket depth, and probing attachment levels were determined at baseline, 3 weeks, and 6 weeks. The composition of the subgingival microflora in the prophied and non‐prophied quadrants was examined by phase contrast microscopy and by immunofluorescence. This study demonstrates that an antimicrobial product delivered by an oral irrigating device could result in significant reductions in plaque, bacterial cell counts, and gingival bleeding and may, therefore, be an effective adjunct to normal oral hygiene.