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Histologic Evaluation of New Attachment Apparatus Formation in Humans
Author(s) -
Bowers Gerald M.,
Chadroff Brian,
Carnevale Robert,
Mellonig James,
Corio Russel,
Emerson Jane,
Stevens Mark,
Romberg Elaine
Publication year - 1989
Publication title -
journal of periodontology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.036
H-Index - 156
eISSN - 1943-3670
pISSN - 0022-3492
DOI - 10.1902/jop.1989.60.12.675
Subject(s) - cementum , periodontal fiber , dentistry , dentin , regeneration (biology) , connective tissue , cementogenesis , clinical attachment loss , dental cementum , pulp (tooth) , dental alveolus , medicine , periodontitis , pathology , biology , microbiology and biotechnology
T here is conflicting evidence regarding the value of graft materials in enhancing the formation of new bone, cementum, and periodontal ligament (new attachment apparatus). Part II of this study compared the healing of intrabony defects with and without the placement of decalcified freeze‐dried bone allograft (DFDBA) in a submerged environment. The most apical level of calculus on the root served as a histologic reference point to measure regeneration on root surfaces exposed to the oral environment. Biopsies were obtained at 6– months and evaluated histometrically by two investigators unaware of the treatment performed. Data from 9 patients with 30 grafted defects and 13 nongrafted defects were submitted for statistical analysis. Results indicate that in a submerged environment significantly more new attachment apparatus ( P <.05) and new bone ( P <.05) formed in grafted than nongrafted sites. Significantly greater loss of alveolar crest height occurred in nongrafted than grafted defects ( P <.05); regeneration of new attachment apparatus, new bone, and new cementum occurred more frequently in grafted than nongrafted defects. There was a greater chance for the regeneration of a connective tissue attachment in nongrafted intrabony defects than in grafted defects; new cellular cementum formed equally well on old cementum, dentin, or both old cementum and dentin in the same defect. The periodontal ligament was oriented parallel, perpendicular, or both parallel and perpendicular in the same defect; and, no extensive root resorption, ankylosis, or pulp death was observed in grafted or nongrafted defects. ( Journal of Periodontology , 1989; 60: 675–682)