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Effect of Citric Acid Treatment on the Migration of Epithelium on Root Surfaces in Vitro
Author(s) -
Larjava Hannu,
Salonen Jukka,
Häkkinen Lari,
Närhi Timo
Publication year - 1988
Publication title -
journal of periodontology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.036
H-Index - 156
eISSN - 1943-3670
pISSN - 0022-3492
DOI - 10.1902/jop.1988.59.2.95
Subject(s) - citric acid , in vitro , epithelium , chemistry , microbiology and biotechnology , biochemistry , biology , medicine , pathology
E xplants of bovine gingival mucosa were cultured for four days on scaled and citric acid‐conditioned root surfaces. Demineralization of the hard tissue with citric acid exposed the collagenous matrix of the root. Undemineralized islands were frequently seen among the collagen fibers of the treated roots. When cultured on scaled, control root surfaces, the epithelium migrated inwards between the connective tissue of the expiant and the root surface. On citric acid‐treated roots, epithelial migration in this direction was rare although it was possible. Citric acid treatment of the substratum directed the epithelium to migrate outwards from the expiant. Only a few of the controls showed epithelial migration to the outward direction. The findings indicate that demineralization of the root surface has an influence on the direction in which the epithelium initially starts to migrate. An induced delay of epithelial migration between the gingival connective tissue and the hard tissue may be favorable for connective tissue attachment to the root surface.