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Pigmentation of the Jawbones and Teeth Secondary to Minocycline Hydrochloride Therapy
Author(s) -
Cale Anne E.,
Freedman Paul D.,
Lumerman Harry
Publication year - 1988
Publication title -
journal of periodontology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.036
H-Index - 156
eISSN - 1943-3670
pISSN - 0022-3492
DOI - 10.1902/jop.1988.59.2.112
Subject(s) - minocycline , medicine , dentistry , dental alveolus , dermatology , chemistry , antibiotics , biochemistry
O ral pigmentation due to minocycline hydrochloride (Minocin ® ) therapy is an unusual and infrequently reported side effect of the drug. This report describes a patient on long‐term minocycline therapy who presented with gingival pigmentation. Upon surgical exploration, the gingiva was noted to be normal in color, but the underlying bone was deeply pigmented. Via fluorescent microscopy, minocycline deposition within the alveolar bone was demonstrated.