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Specific Herpes Simplex Virus Antigen in Human Gingiva
Author(s) -
Ehrlich J.,
Cohen G. H.,
Hochman N.
Publication year - 1983
Publication title -
journal of periodontology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.036
H-Index - 156
eISSN - 1943-3670
pISSN - 0022-3492
DOI - 10.1902/jop.1983.54.6.357
Subject(s) - stratum spinosum , stratum granulosum , herpes simplex virus , antigen , hsl and hsv , staining , virus , virology , medicine , biology , immunology , pathology , stratum corneum
H erpes simplex virus type 1 (HSV‐1) specific antigens were found to be present in the sulcular epithelial cells of patients that were undergoing periodontal treatment. Four out of 14 cases were positive to specific HSV‐1 antigen, as demonstrated by the indirect immunofluorescent assay. No nuclear staining was seen in any epithelial cells. These observations seem to indicate that the viral genome resides in the sulcular epithelial cells of the gingiva and is possibly localized in the stratum granulosum and spinosum.