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Salivary ABO Antibodies and Periodontal Disease
Author(s) -
Hardman Patrick K.,
Hardman Jill T.
Publication year - 1983
Publication title -
journal of periodontology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.036
H-Index - 156
eISSN - 1943-3670
pISSN - 0022-3492
DOI - 10.1902/jop.1983.54.6.351
Subject(s) - saliva , medicine , abo blood group system , periodontal disease , titer , volunteer , antibody , antibody titer , periodontitis , gastroenterology , agglutinin , immunology , dentistry , biology , agronomy , lectin
T he purpose of this study was to determine and to compare the titers of salivary anti‐A and anti‐B antibodies in two groups of patients with periodontal disease as measured by Russell's Periodontal Index (PI). Forty volunteer subjects, who were new patients assigned to a screening clinic, were selected for the study based on the following criteria: (1) blood group, (2) medical history, (3) age and (4) periodontal condition. One group of patients ( N = 20) had a PI of less than 2.0 and the other group of patients ( N = 20) had a PI of greater than 4.0. Following screening, a 10‐ml sample of unstimulated whole saliva was collected, centrifuged and frozen. Within 30 days the saliva was thawed, titrated and tested for presence of anti‐A and anti‐B. Saliva agglutinin titers were determined using a variation of previous testing techniques. Statistically significant differences between the two groups were not obtained in the titers of salivary anti‐A (U = 192.5; P > 0.1) or the titers of salivary anti‐B (U = 162.8; P > 0.1). All 40 group O patients were found to have anti‐A and anti‐B in their saliva.