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Effectiveness of Routine Periodontal Treatment With and Without Adjunctive Metronidazole Therapy in a Sample of Mentally Retarded Adolescents
Author(s) -
Clark D. Christopher,
Shenker Stephanie,
Stulginski Phillip,
Schwartz Stephane
Publication year - 1983
Publication title -
journal of periodontology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.036
H-Index - 156
eISSN - 1943-3670
pISSN - 0022-3492
DOI - 10.1902/jop.1983.54.11.658
Subject(s) - metronidazole , mentally retarded , medicine , placebo , periodontal disease , adjunctive treatment , clinical trial , dentistry , antibiotics , psychology , alternative medicine , developmental psychology , pathology , microbiology and biotechnology , biology
A sample of mentally retarded adolescents with moderate periodontal disease was given conventional treatment with and without adjunctive metronidazole therapy following consent of guardians. Antibiotics or placebo tablets were taken 1 week following prophylaxis in a double blind clinical trial. Six months after the baseline examinations, there were no significant differences between the treatment and control groups in the mean attachment level or the proportions of microorganisms in subgingival pockets.