Premium
IgG and IgG Subclasses in Human Periodontosis (Juvenile Periodontitis): Serum Concentrations
Author(s) -
Waldrop Thomas C.,
Mackler Bruce F.,
Schur Peter
Publication year - 1981
Publication title -
journal of periodontology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.036
H-Index - 156
eISSN - 1943-3670
pISSN - 0022-3492
DOI - 10.1902/jop.1981.52.2.96
Subject(s) - radial immunodiffusion , subclass , periodontitis , immunodiffusion , antibody , immunoglobulin g , immunology , juvenile , medicine , biology , chemistry , genetics
S erum immunoglobulin (Ig) concentrations of IgG and the IgG subclasses (IgGl, IgG2, IgG3, IgG4) in periodontosis (juvenile periodontitis) patients were examined and compared to those of normal nondiseased patients. Ig titers were determined by radial immunodiffusion. The mean serum concentration of IgG, although within the normal range, was significantly greater (P < 0.01) in periodontosis patients compared to nondiseased patients. In contrast, there were no significant differences in serum IgG subclass levels between groups.