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Tetracycline: A Clinical Study to Determine its Effectiveness as Long‐Term Adjuvant
Author(s) -
Scopp Irwin Walter,
Froum Stuart J.,
Sullivan Michael,
Kazandjian Gregory,
Wank David,
Fine Albert
Publication year - 1980
Publication title -
journal of periodontology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.036
H-Index - 156
eISSN - 1943-3670
pISSN - 0022-3492
DOI - 10.1902/jop.1980.51.6.328
Subject(s) - placebo , tetracycline , medicine , placebo group , curettage , surgery , dentistry , gastroenterology , antibiotics , biology , pathology , microbiology and biotechnology , alternative medicine
A random double blind crossover study of patients on the effects of tetracycline therapy over a 3‐month period revealed that there were no significant differences between the placebo group and tetracycltne‐treated groups in relation to (1) Gingival Index, (2) Debris Index and (3) Papillary Bleeding. A marked improvement in the Gingival Index occurred after 3 months of treatment in each group resulting from curettage and home care. Papillary bleeding was significantly reduced after 3 months of treatment in the tetracycline group and similar trends were observed in the placebo group. The Debris Index in both experimental and placebo groups showed no significant change after treatment for 3 months. The data suggest that tetracycline therapy does not appreciably alter either the Gingival Index, Debris Index, or the Papillary Bleeding Index over a 3‐month period.