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Xenogeneic Implants in Primates: Collagen and Chondroitin Sulfate
Author(s) -
Skinner Raymond A.,
Toto Patrick D.,
Gargiulo Anthony W.
Publication year - 1976
Publication title -
journal of periodontology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.036
H-Index - 156
eISSN - 1943-3670
pISSN - 0022-3492
DOI - 10.1902/jop.1976.47.4.196
Subject(s) - chondroitin sulfate , implant , curettage , dentistry , wound healing , medicine , biomedical engineering , pathology , surgery , anatomy , glycosaminoglycan
This study was undertaken to examine histologically, in monkeys, the sequential healing phenomena of created two-walled osseous defects, which have been corrected by purified collagen and a mixed isomer of chondroitin sulfate. Four adult rhesus monkeys were used as experimental models and provided 23 specimens, from 0 to 56 days postoperatively. Sixteen of these served as implant specimens, and seven served as control specimens in which defects were corrected by curettage only. Two types of implant materials were utilized. The implants were compatible with osteogenesis. The two implant materials themselves did not differ in the healing events.