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Studies of Herpes Simplex Virus and Interferon in Human Gingival Cell Cultures
Author(s) -
Gordon George D.,
Uhlendorf Carol P.,
Baer Paul N.,
Baron Samuel
Publication year - 1975
Publication title -
journal of periodontology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.036
H-Index - 156
eISSN - 1943-3670
pISSN - 0022-3492
DOI - 10.1902/jop.1975.46.2.86
Subject(s) - herpes simplex virus , virology , interferon , simplexvirus , medicine , virus , microbiology and biotechnology , biology , herpesviridae , viral disease
Cultures of human gingival fibroblast cells from patients with a positive or negative history of recurrent herpes simplex virus (HSV) infection were compared with respect to susceptibility to HSV infection and interferon activity. There was a possible inverse relationship between interferon sensitivity of gingival fibroblast cells and a clinical history of recurrent disease. No correlation was found between prior infection and other parameters of interferon activity or susceptibility of the cells to HSV.

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