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Evaluation of dicloran's contribution to the mutagenic activity of Cristais river, Brazil, water samples
Author(s) -
de Oliveira Danielle Palma,
Sakagami Maureen,
Warren Sarah,
Kummrow Fábio,
Umbuzeiro Gisela de Aragão
Publication year - 2009
Publication title -
environmental toxicology and chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.1
H-Index - 171
eISSN - 1552-8618
pISSN - 0730-7268
DOI - 10.1897/09-103.1
Subject(s) - mutagen , salmonella , environmental chemistry , chemistry , biology , carcinogen , bacteria , organic chemistry , genetics
2,6‐Dichloro‐4‐nitroaniline (dicloran) is a mutagenic aromatic amine used as an agricultural fungicide and in the synthesis of disperse dyes. It is a known mutagen ( Salmonella /microsome assay) in strains TA98 and TA100. Dicloran was initially detected, but not quantified, in the Cristais River, Brazil. The objective of the present study was to estimate the contribution of dicloran to mutagenic activity in samples from this river. Dicloran was found in the raw water at 0.14 μg/L but not in the treated water. Comparison of mutagenic potencies in Salmonella strain YG1041 for dicloran and the river water sample indicated that dicloran contributed less than 0.1% of total mutagenic activity.