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A novel method using cyanobacteria for ecotoxicity test of veterinary antimicrobial agents
Author(s) -
Ando Tomonori,
Nagase Hiroyasu,
Eguchi Kaoru,
Hirooka Takashi,
Nakamura Takanori,
Miyamoto Kazuhisa,
Hirata Kazumasa
Publication year - 2007
Publication title -
environmental toxicology and chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.1
H-Index - 171
eISSN - 1552-8618
pISSN - 0730-7268
DOI - 10.1897/06-195r.1
Subject(s) - ecotoxicity , cyanobacteria , antimicrobial , microcystis aeruginosa , microcystis , algae , ec50 , biology , bioassay , toxicity , microbiology and biotechnology , chemistry , food science , botany , bacteria , ecology , biochemistry , in vitro , organic chemistry , genetics
The effect of antimicrobial agents for veterinary use on the growth of cyanobacteria was investigated by measuring minimum inhibitory concentration, medium effective concentration (EC50), and no‐observed‐effect concentration of seven antimicrobial agents for eight cyanobacteria. The results demonstrated that the seven antimicrobial agents, even at low concentrations, inhibited the growth of cyanobacteria. Microcystis aeruginosa and Synechococcus sp. had the highest sensitivity to the antimicrobial agents used in the present study. It is considered that the utilization of cyanobacteria would enable easy and highly sensitive assessment of the toxicity of such chemicals as antimicrobial agents. We suggest that cyanobacteria be used for ecotoxicity test in addition to the hitherto established method that uses green algae.