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Response of Aedes aegypti (Diptera: Culicidae) larvae to three xenobiotic exposures: Larval tolerance and detoxifying enzyme activities
Author(s) -
Boyer Sebastien,
David JeanPhilippe,
Rey Delphine,
Lemperiere Guy,
Ravanel Patrick
Publication year - 2006
Publication title -
environmental toxicology and chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.1
H-Index - 171
eISSN - 1552-8618
pISSN - 0730-7268
DOI - 10.1897/05-267r2.1
Subject(s) - aedes aegypti , larva , xenobiotic , biology , aedes , toxicology , enzyme , zoology , ecology , biochemistry
The ability of mosquito larvae to tolerate toxic compounds (temephos, Bacillus thuringiensis var. israelensis , toxic vegetable leaf litter) was examined on a laboratory larval strain of Aedes aegypti L. Bioassays and detoxifying enzyme activity measurements were performed to compare tolerance/resistance capacities. The possibility of a functional plasticity of detoxifying equipment was investigated through experimental determination of the inductive effect of each xenobiotic within a given generation. In the same way, the selective effect of a toxic leaf litter was also investigated along successive generations. Results revealed that differential cytochrome P450 monooxygenase, esterase, and glutathione S ‐transferase activity levels correlated with the bioassay results. Both induction and selection increased larval tolerance to the xenobiotics used and increased the levels of larval detoxifying enzyme activities.