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Patterns of genotoxicity and contaminant exposure: Evidence of genomic instability in the marsh frogs ( rana ridibunda ) of sumgayit, azerbaijan
Author(s) -
Matson Cole W.,
Palatnikov Grigoriy M.,
McDonald Thomas J.,
Autenrieth Robin L.,
Donnelly K.C.,
Anderson Todd A.,
Canas Jaclyn E.,
Islamzadeh Arif,
Bickham John W.
Publication year - 2005
Publication title -
environmental toxicology and chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.1
H-Index - 171
eISSN - 1552-8618
pISSN - 0730-7268
DOI - 10.1897/04-250r1.1
Subject(s) - rana ridibunda , genotoxicity , mercury (programming language) , marsh , wetland , micronucleus test , environmental chemistry , micronucleus , ecotoxicology , pesticide , population , sediment , biology , environmental science , ecology , chemistry , zoology , toxicity , demography , paleontology , organic chemistry , sociology , computer science , programming language
The wetlands of Sumgayit in the Azerbaijan Republic contain complex mixtures of contaminants, including polycyclic aromatic hydrocarbons (PAHs), mercury, organochlorine pesticides, and polychlorinated biphenyls. Marsh frogs ( Rana ridibunda ) were collected from several contaminated wetlands within the city as well as from two reference sites outside the city. Sediment samples revealed heterogeneous patterns of PAH and mercury concentrations throughout Sumgayit, with the highest levels occurring east of the Sumgayit River, within the industrial zone. Flow cytometry and micronucleus assay revealed elevated estimates of genetic damage in frogs from the wetlands east of the Sumgayit River compared to frogs from the reference sites. Flow cytometric data showed a significant correlation with sediment mercury concentrations, whereas population micronucleus frequencies were significantly correlated with high‐molecular‐weight PAHs.