Open AccessMETHODS OF PRECLINICAL DIAGNOSIS OF PREECLAMPSIA. COMPARISON OF BIOCHEMICAL AND INSTRUMENTAL METHODS OF EXAMINATION
Author(s) -
Saida Kh. Eristova
Publication year - 2018
Publication title -
arhiv akušerstva i ginekologii im. v.f. snegireva
Language(s) - English
Resource type - Journals
eISSN - 2687-1386
pISSN - 2313-8726
DOI - 10.18821/2313-8726-2018-5-3-128-131
Subject(s) - preeclampsia , medicine , obstetrics , placenta , pregnancy , ultrasound , gestation , diagnostic test , gynecology , radiology , fetus , biology , pediatrics , genetics
The review presents current information on the predictive diagnosis of preeclampsia. The data of instrumental and laboratory diagnostics are described. Laboratory diagnostics includes such biochemical markers as PAPP-A, PIGF, VEGF, sFlt-1, sEng, NSE; instrumental diagnostics consists of ultrasound evaluation of placental structure, ultrasound dopplerometry of uterine arteries and determination of the index of vascularization of the placenta. Not all methods of the examination presented by the author have diagnostic value in the clinical use. Biochemical markers present the most accurate diagnostic picture. It is necessary to evaluate sFlt-1, PIGF and other markers in dynamics since their change with the increase in the gestation age differs significantly from the change in those in women with normal pregnancy.