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DEXAMETHASONE AND POSTOPERATIVE ANALGESIA
Author(s) -
А. М. Овечкин,
Овечкин Алексей Михайлович,
М Е Политов,
Политов М. Е
Publication year - 2018
Publication title -
regionarnaâ anesteziâ i lečenie ostroj boli
Language(s) - English
Resource type - Journals
eISSN - 2687-1394
pISSN - 1993-6508
DOI - 10.18821/1993-6508-2018-12-3-148-154
Subject(s) - dexamethasone , medicine , anesthesia , analgesic , systemic administration , local anesthetic , onset of action , orthopedic surgery , anesthetic , surgery , microbiology and biotechnology , in vivo , biology
The review contains the analysis of analgesic and opioid-saving action of dexamethasone in its systemic administration. These effects are most evident in the preventive administration of the drug 1.5-2 hours before surgery. The most promising area of application of dexamethasone as a component of anesthetic support is laparoscopic surgery. In the orthopedic clinic, the use of dexamethasone can increase the duration of action of peripheral nerve blockades and plexuses (both sensory and motor block), while perineural administration (addition to the local anesthetics) has no advantages over intravenous injection. Single administration of a standard dose of dexamethasone (8 mg) is not accompanied by the occurrence of clinically significant side effects.

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