
DEXMEDETOMIDINE AS A COMPONENT OF ANESTHESIAAND PROMISING BASE FOR OPIOID FREE ANALGESIA
Author(s) -
А. М. Овечкин,
М Е Политов,
Е Л Буланова
Publication year - 2018
Publication title -
regionarnaâ anesteziâ i lečenie ostroj boli
Language(s) - English
Resource type - Journals
eISSN - 2687-1394
pISSN - 1993-6508
DOI - 10.18821/1993-6508-2018-12-2-82-90
Subject(s) - dexmedetomidine , anesthesia , medicine , opioid , sedation , receptor
Data suggests that intravenous infusion of dexmedetomidine, started 15-20 minutes before the induction of general anesthesia, can significantly reduce the doses of intravenous anesthetics, MAC of inhalation anesthetics, and requirements in opioid analgesics during the surgery. Intraoperative infusion of dexmedetomidine prolongs the time of the first requirement of analgesics after surgery, reduces the average pain intensity in the early postoperative period, and also requirements in opioid analgesics.