Open AccessTHE ROLE OF MONOAMINES IN REGULATION OF ANGIOGENESIS AND PROSPECTS OF THEIR APPLICATION IN RETINOPATHY OF PREMATURITY
Author(s) -
Л А Катаргина,
Е. В. Денисова,
Н А Осипова,
A. Yu. Panova
Publication year - 2018
Publication title -
rossijskaâ pediatričeskaâ oftalʹmologiâ
Language(s) - English
Resource type - Journals
eISSN - 2412-432X
pISSN - 1993-1859
DOI - 10.18821/1993-1859-2018-13-2-76-80
Subject(s) - retinopathy of prematurity , blindness , neonatology , childhood blindness , medicine , angiogenesis , pediatrics , gestational age , low birth weight , intensive care medicine , optometry , pregnancy , biology , genetics
Retinopathy of prematurity is the main cause of visual impairment and blindness in infants with low birth weight and preterm gestational age, in spite of the achievements in neonatology and wide applying of diagnostic and treatment guidelines. The pathogenetic role of VEGF is determined in course of normal angiogenesis and in retinopathy of prematurity. Scientists continue the search of another significant vasoprolifirative factors and methods how to inhibit them. This review is devoted to monoamines’ role in angiogenesis. The search for the relevant literature was carried out using the Medline database.