Open AccessEXPERIMENTAL STUDY OF THE USE OF BIODEGRADABLE COLLAGEN MEMBRANES IN THE CLOSURE OF POSTOPERATIVE DEFECTS OF THE RABBIT ORAL MUCOUS MEMBRANE
Author(s) -
Svetlana Tarasenko,
А. Б. Шехтер,
Elena Istranova,
Е. А. Морозова,
Nataliya A. Blagushina
Publication year - 2019
Publication title -
rossijskij stomatologičeskij žurnal
Language(s) - English
Resource type - Journals
eISSN - 2413-2934
pISSN - 1728-2802
DOI - 10.18821/1728-2802-2019-23-5-192-196
Subject(s) - membrane , mucous membrane , wound healing , granulation tissue , medicine , dentistry , hard palate , surgery , biomedical engineering , pathology , chemistry , biochemistry
The aim is to increase the efficiency of surgical treatment of dental patients with the use of bioresorbable collagen membranes to close postoperative wound defects of the oral mucous membrane. Material and methods. The experimental model was created on 18 laboratory rabbits. The animals were divided into 3 groups: in the control group the healing of the mucous membrane defect on the hard palate was carried out by secondary tissue tension, in the research groups - under the xenopericardium membrane (1) and collagen membrane (2). The morphological study was based on biopsy of all animals' mucous membranes of the hard palate. Microvolume slices 4-5 microns thick were examined on a light microscope. Results. The results testify to the formation of granulation tissue an d epithelization of defects both in the research groups and in the control group. When using collagen materials, a noticeable activatio n of the wound process, shortening of epithelialization were found. A certain advantage of pericardium in activation of wound repair was noted. Conclusion. Application of collagen membranes can be recommended as a method of choice at closing of postoperative defects of the oral mucous membrane after clinical studies.