Open AccessNEW OPPORTUNITIES LOCAL MEDICAL TREATMENT OF PERIODONTAL DISEASES (MICROBIOLOGICAL RATIONALE)
Author(s) -
A. N Kalinina,
I. S Lasko,
В.Н. Царев,
Egor E. Olesov,
A. F. Stepanov,
E. V Glazkova,
В. Н. Олесова
Publication year - 2018
Publication title -
rossijskij stomatologičeskij žurnal
Language(s) - English
Resource type - Journals
eISSN - 2413-2934
pISSN - 1728-2802
DOI - 10.18821/1728-2802-2018-22-4-180-183
Subject(s) - fusobacterium nucleatum , aggregatibacter actinomycetemcomitans , staphylococcus aureus , microbiology and biotechnology , stationary phase , lag time , biology , medicine , chemistry , dentistry , periodontitis , bacteria , porphyromonas gingivalis , chromatography , genetics , biological system
The article presents the results of a microbiological experiment to study the sensitivity of periodontal pathogens to coniferous polyprenols in the preparation of “Solagift”. The optica density of clinical isolates Streptococcus constellatus; Staphylococcus aureus; Fusobacterium nucleatum; Aggregatibacter actinomycetemcomitans during cultivation with the addition of polyprenol concentrate 1:5 was measured during 3-7 days. Comparison criteria: the change in the phase of adaptation (lag-phase), the phase change of geometric growth, the amplitude of the peak phase of geometric growth, the duration of the stationary phase, the period of the withering away of culture. In comparison with the parameters of periodontal pathogens in the control, the presence of coniferous polyprenols led to a significant decrease in the activity of all microbes according to all criteria, especially Staphylococcus aureus, whose growth was completely suppressed.