Open AccessA RANDOMIZED STUDY OF THE SAFETY AND EFFECTIVENESS OF PRODUCTS BASED ON STABILIZED HYALURONIC ACID FOR THE CORRECTION OF INVOLUTIONAL CHANGES IN FACE AND NECK
Author(s) -
Gulya Sh. Zakirova,
Elena Gubanova,
В В Гладько,
Ada A. Vavilova,
Inna V. Ilina
Publication year - 2018
Publication title -
rossijskij žurnal kožnyh i veneričeskih boleznej
Language(s) - English
Resource type - Journals
eISSN - 2412-9097
pISSN - 1560-9588
DOI - 10.18821/1560-9588-2018-21-1-51-53-60
Subject(s) - medicine , cosmetology , hyaluronic acid , randomization , randomized controlled trial , soft tissue , surgery , dermatology , anatomy , art , visual arts
According statistics, fillers occupy a leading position among non-surgical procedures. Despite their diversity in Russia, the evidence base for the treatment of age-related changes in the skin according to number of clinical and instrumental methods in the diagnostic is not enough. The combination of hyaluronic acid (HA) injections with fillers is pathogenetically justified. Therefore the search for scientifically based protocols for the correction of skin ageing is an actual trend in cosmetology and dermatology. Purpose. To assess the safety and effectiveness of correction of involuntary changes in face and neck skin with drugs based on stabilized hyaluronic acid. Material and methods. 35 women aged 30-65 years were enrolled into two groups by simple randomization. Group I received monotherapy with HA fillers, patients of group II - complex rejuvenation therapy for face and neck: fillers and course of vitalization stabilized HA. The efficasy was assessed according to the Global Aesthetic Improvement Scale (GAIS) on the 1st(M01), 2nd (M02), 3rd (M3), 6th (M06) month of complex therapy instrumental methods (cutometry, corneometry). Safety was assessed during 12 months of follow-up and ultrasound examination of the facial soft tissues. Results. The safety and efficacy injections of stabilized HA have been clinically confirmed. The advantages of complex therapy of fillers and the course of vitalization are shown