Open AccessPSORIASIS ADJUVANT THERAPY
Author(s) -
А. Л. Бакулев,
S. S Krachevnya,
И. А. Игонина,
Е. М. Галкина,
Sergei R. Utz
Publication year - 2017
Publication title -
rossijskij žurnal kožnyh i veneričeskih boleznej
Language(s) - English
Resource type - Journals
eISSN - 2412-9097
pISSN - 1560-9588
DOI - 10.18821/1560-9588-2017-20-6-355-359
Subject(s) - medicine , psoriasis , lotion , dermatology , methotrexate , adjuvant therapy , chemotherapy , pharmacology
60 adult patients with moderate severity of psoriasis in progression phase of dermatosis were observed. In the combined therapy of methotrexate and topical glucocorticosteroid, the patients were additionally treated with Cetaphil® Restoraderm™ Skin restoring moisturizing lotion (hereinafter referred to as Cetaphil® RestoradermTM moisturizing lotion). In the course of treatment a multivariate evaluation of the functional and morphological parameters of the skin using the SOFT PLUS TOP apparatus (sebumetry, corneometry and elastometry), as well as assessment of severity, prevalence of psoriasis (PASI), quality of life of patients (DLQI) on the 14th and 28th days of observation was performed. It was found that the inclusion of moisturizing lotion in the combined therapy led to an earlier beginning of stabilization and regression of the psoriatic process, relief of subjective disorders, improvement of the quality of life of patients with psoriasis. Also statistically significant reduction of skin dryness and normalization of moistness and elasticity, which testifies to the expressed sebouregulating, elastogenic and moisturizing effects of this topical remedy, were observed.