Open AccessTHE USE OF INTRAVENOUS IMMUNOGLOBULIN PENTAGLOBIN IN THE COMPLEX TREATMENT OF SEVERE COMMUNITY-ACQUIRED PNEUMONIA IN CHILDREN
Author(s) -
Aizarkhanum Yu. Arslanova,
А. М. Алискандиев,
M. I. Izrailov,
Z. A. Aliskandieva,
Fazilat Ismailova
Publication year - 2019
Publication title -
rossijskij pediatričeskij žurnal
Language(s) - English
Resource type - Journals
eISSN - 2413-2918
pISSN - 1560-9561
DOI - 10.18821/1560-9561-2019-22-1-28-32
Subject(s) - etiology , pneumonia , medicine , dominance (genetics) , community acquired pneumonia , septic shock , antibody , pseudomonas aeruginosa , immunology , pediatrics , biology , sepsis , bacteria , biochemistry , genetics , gene
There are presented data from a comprehensive examination and treatment of 30 children with community-acquired pneumonia (CAP). For the treatment of young children with focal-confluent forms of CAP and the clinical manifestations of infectious-septic shock, Pentaglobin preparations containing IgM were used. Severe CAP with a tendency to destruction was more often observed in cases with the dominance of gram-negative flora in the etiological structure, most often detected in the foothill zone (18.2% of children), in the middle mountain zone - in- 13.3%, in the low-grade zone - in 5% of children. Pseudomonas aeruginosae was more commonly seeded in children in the foothill zone (12.5%), while in children living in the lowland and middle mountain zone in 2.5% and 6.6% correspondingly. The authors showed the preparation of intravenous immunoglobulin Pentoglobin is a safe, effective, easily tolerated means of etiotropic and pathogenetic therapy of severe CAP, caused more often by gram-negative and gram-positive bacterial microbiota.