Open AccessFEATURES OF THE INTESTINAL MICROBIOTA IN CHILDREN WITH ALLERGIC DISEASES AND VARIOUS BODY WEIGHT
Author(s) -
С А Мазурина,
О. В. Максимова,
Valentina Gervazieva
Publication year - 2019
Publication title -
rossijskij pediatričeskij žurnal
Language(s) - English
Resource type - Journals
eISSN - 2413-2918
pISSN - 1560-9561
DOI - 10.18821/1560-9561-2017-20-4-202-206
Subject(s) - bacteroides , atopic dermatitis , allergy , immunology , asthma , etiology , medicine , obesity , microbiome , gut flora , biology , bacteria , pathology , bioinformatics , genetics
The data of the bacteriological study of the intestinal microbiota in children with allergic diseases and various body weights are presented. A total of 106 children were examined, including 58 with allergic diseases (bronchial asthma, allergic rhinitis, atopic dermatitis). All children were divided into groups, depending on the weight of the body, taking into account the gender and age of the child. Allergic pathology and obesity were established to be interrelated in different ways with changes in the number of obligate and facultative microbiota of children. Allergic diseases in children are associated with a decreased number of Bacteroides spp. and the presence of S. aureus and Bacillus sp., regardless of body weight. Obesity, in turn, is characterized by a decrease in Bacteroides spp., especially in healthy children, and an increase in the number of Clostridium sp., regardless of the presence of allergies. The obtained data testify to the role of microorganisms in the etiology and pathogenesis of these diseases, the key link of which is chronic systemic inflammation.