Open AccessURTICARIA IN CHILDREN: CLINICAL AND PATHOGENETIC VARIANTS, DIAGNOSIS AND TREATMENT
Author(s) -
И.И. Балаболкин
Publication year - 2019
Publication title -
rossijskij pediatričeskij žurnal
Language(s) - English
Resource type - Journals
eISSN - 2413-2918
pISSN - 1560-9561
DOI - 10.18821/1560-9561-2017-20-2-122-128
Subject(s) - chronic urticaria , medicine , pharmacotherapy , pathogenesis , leukotriene receptor , immunology , immunoglobulin e , dermatology , leukotriene , asthma , antibody
There is presented the modern concept of pathogenesis of urticaria in children and the participation of immunopathological responses in its development, the influence of physical factors, clinical and pathogenetic variants of acute and chronic urticaria, its diagnosis and treatment. The expediency of differentiated therapy, based on the severity of urticaria, features of its development and response to treatment, is shown. The effectiveness of the treatment of urticaria in children with antihistamines, leukotriene receptor antagonists and glucocorticosteroids was noted. Positive result of anti-IgE-therapy was noted in children with severe forms of urticaria, resistant to pharmacotherapy.