Open AccessInflammatory demyelinating polyneuropathies in children
Author(s) -
А. В. Климкин,
В. Б. Войтенков,
Н В Скрипченко
Publication year - 2019
Publication title -
rossijskij pediatričeskij žurnal
Language(s) - English
Resource type - Journals
eISSN - 2413-2918
pISSN - 1560-9561
DOI - 10.18821/1560-9561-2016-19-3-183-191
Subject(s) - polyradiculoneuropathy , chronic inflammatory demyelinating polyneuropathy , etiology , medicine , guillain barre syndrome , polyneuropathy , pathogenesis , disease , demyelinating disease , immunology , myelin , cerebrospinal fluid , pathology , central nervous system , antibody
There are presented data on clinical variants and peculiarities of the course of acute demyelinating inflammatory polyneuropathy in children. This disease is the acute post-infectious immune-mediated polyradiculoneuropathy characterized by the destruction of myelin ofperipheral nerves and manifested by the syndrome of symmetrical polyneuropathy with motor, sensor, autonomous disturbances and albuminocytologic dissociation in cerebrospinal fluid. This disease is known to be commonly developed during 2-4 weeks with following stage of stabilization and then improvement. There are considered issues of etiology and pathogenesis of Guillian-Barre syndrome, with the accents on pediatric aspects. There are given data on chronic demyelinating inflammatory polyneuropathy andM. Fischer syndrome also. There are described neurophysiological criteria for demyelinating disorders in children and considered issues of their management.