Open AccessEfficacy of Miramistin in the correction of the oropharynx microbiocenosis in sickly children
Author(s) -
И. В. Николаева,
Ekaterina S. Gerasimova,
T. Yu. Pavlova
Publication year - 2019
Publication title -
rossijskij pediatričeskij žurnal
Language(s) - English
Resource type - Journals
eISSN - 2413-2918
pISSN - 1560-9561
DOI - 10.18821/1560-9561-2016-19-1-9-14
Subject(s) - tonsillitis , medicine , antibiotics , pharyngitis , respiratory tract , microbiology and biotechnology , antimicrobial , pathogenic bacteria , bacteria , respiratory system , biology , genetics
There are presented data of the analysis of the composition of the oropharynx microbiota and antimicrobial resistance of opportunistic bacteria isolated in sickly children to determine the effectiveness of the preparation Miramistin. There was executed a bacteriological study of the microflora of the oropharynx in 71 children with respiratory recurrent infections (RIRs). There was determined the resistance of isolated species ofpathogens of respiratory infections to antibiotics of different classes. Children suffering from RIRs were found to have species and and quantitative disorders of the pattern ofpharynx microflora in 90,2% of cases. In cultures from oropharyngeal mucosa there were isolated 15 types of potentially pathogenic bacteria, among them there were dominated: S. aureus (31%), Haemophilus influenzae (11,3%),) Strept. pyogenes (11,3%) and Strept. pneumoniae (8,4%). All of the isolated in sickly children strains of S. aureus and Strept. pyogenes (including strains resistant to antibiotics and bacteriophages) were susceptible to Miramistin. There was proved high efficiency and safety of Miramistin in the complex therapy of various forms of inflammatory diseases oa upper respiratory tract: angina, chronic tonsillitis, pharyngitis and nasopharyngitis in children. It is recommended to always include Miramistin in the complex treatment of infectious and inflammatory diseases of the oropharynx.