Open AccessFEBRILE INFECTION-RELATED EPILEPSY SYNDROME (FIRES): COMPLICATED DIAGNOSIS AND CASE REPORT
Author(s) -
Armen K. Shakaryan,
А. А. Холин,
Н. В. Туркот,
D. V. Shakhmaeva,
Inna Mitrofanova
Publication year - 2018
Publication title -
èpidemiologiâ i infekcionnye bolezni
Language(s) - English
Resource type - Journals
eISSN - 2411-3026
pISSN - 1560-9529
DOI - 10.18821/1560-9529-2018-23-3-142-148
Subject(s) - status epilepticus , medicine , epilepsy , disease , refractory (planetary science) , pediatrics , intensive care medicine , pathogenesis , pathology , psychiatry , physics , astrobiology
Febrile infection-related epilepsy syndrome (FIRES) is an acute disease provoked by the nonspecific febrile illness with the development of refractory status epilepticus. It frequently occurs in previously healthy children. The pathogenesis of this syndrome is still unknown. The leading initial symptoms include acute fever, seizures, consciousness disorders and imitate neuroinfection or autoimmune pathology of CNS. These features make diagnosis extremely difficult, and there are in addition some difficulties with the verification of the diagnosis. Interpretation of MRI results allows identifying involved parts of the brain. However, the EEG record pattern is not precise. We report a clinical case of FIRES occurred in a 14-year-old previously healthy boy. The disease began similarly to an acute neuroinfection disease with prolonged refractory status epilepticus